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Doctors cautioned over adverse effects of 24 drugs

New Delhi: Indian Pharmacopoeia Commission (IPC) has named 24 drugs that have adverse reactions and that doctors must therefore prescribe with caution.

The adverse drug reactions (ADRs) have been reported by government and private doctors to IPC under the Pharmacovigilance Programme of India (PvPI).

IPC has recommended to the Central Drugs Standard Control Organisation (CDSCO) for appropriate actions against the 24 drugs.

Reaction to a drug like carbamazepine can cause Stevens-Johnson Syndrome where both layers of the skin are burnt. CDSCO has recommended HLA B 1502 as a screening test to be done before giving this drug.

Ranitidine is found to cause cardiac arrest, anti-rabies vaccine can lead to acute skin infections, and itraconazole and phenytoin are also found to cause severe rashes in the body.

The CDSCO has directed drug companies to include this information in the literature and on labels to avoid any problems, reports Deccan Chronicle.

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