New treatment for brittle bone disease found

Tuesday, August 13, 2013

London: A new treatment for children with brittle bone disease has been developed by the University of Sheffield and Sheffield Children’s Hospital.

Nick Bishop

Nick Bishop

The study of the new treatment for children with the fragile bone disease Osteogenesis Imperfecta is published in The Lancet.

According to the researchers, this is the first study to clearly demonstrate that the use of the medicine risedronate can not only reduce the risk of fracture in children with brittle bones but also have rapid action – the curves for fracture risk begin to diverge after only 6 weeks of treatment.

Nick Bishop, professor of paediatric bone disease at the University of Sheffield, said: “We wanted to show that the use of risedronate could significantly impact on children’s lives by reducing fracture rates – and it did.

“The fact that this medicine can be given by mouth at home (other similar medicines are given by a drip in hospital) makes it family-friendly.”

The study, funded by the Alliance for Better Bone Health, trialled children with Osteogenesis Imperfecta aged 4-15 years and showed that oral risedronate reduced the risk of first and recurrent clinical fractures and that the drug was generally well tolerated.

Categories: Orthopaedics, RESEARCH

Tags: , , , , ,

  More from Orthopaedics

Why some dental implants work and others don’t

New technology switches on cell’s bone repairing ability

Doctors coin new terminology to describe a case of severe kyphosis with abdominal compression

Antibiotics after knee and hip surgery: Are they effective?

Number of people at high risk of fracture set to double by 2040

Study finds some physicians using unnecessary, potentially harmful imaging for acute lower back pain

Comments »

No comments yet.

Name (required)
E-mail (required - never shown publicly)
Your Comment (smaller size | larger size)
You may use <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong> in your comment.